Article
Association of genetic variations in TCF7L2, SLC30A8, HHEX, LOC387761, and EXT2 with Type 2 diabetes mellitus in Tunisia.
Genetic testing and molecular biomarkers - 1 Jun 2011
Kifagi Chamseddine, Makni Kaouthar, Boudawara Mouhamed, Mnif Fatma, Hamza Naziha, Abid Mouhamed, Granier Claude, Ayadi Hammadi
Abstract excerpt
AIM: In recent genome-wide association studies, genetic variants in TCF7L2, SLC30A8, HHEX, LOC387761, and EXT2 were associated with risk for type 2 diabetes mellitus (T2DM). We aimed at investigating the association of these single-nucleotide polymorphisms (SNPs) with T2DM and defining their corresponding allelic and genotypic combinations in the Tunisian population. We also tried to determine the effect of R325W...
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