Article
The glycoprotein-processing inhibitors bromoconduritol and N-methyl-1-deoxynojirimycin alter the adhesion phenotype of skeletal myoblasts.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Dec 1990
Trudel G C, Holland P C
Abstract excerpt
Treatment of chick myoblasts with the glucosidase inhibitors bromoconduritol (BCD) or N-methyl-1-deoxynojirimycin (MDJN), but not the mannosidase I inhibitor 1-deoxymannojirimycin (ManDJN), decreased their rate of adhesion to fibronectin and laminin and increased their rate of adhesion to collagen types I and IV. The adhesion of chick myoblasts to fibronectin, collagen type IV, and laminin was predominantly...
Topics
- 1-Deoxynojirimycin
- Amino Acid Sequence
- Animals
- Cell Adhesion
- Cell Differentiation
- Cell Fusion
- Chick Embryo
- Collagen
- Cyclohexenes
- Extracellular Matrix
- Fibronectins