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Article

Potential Therapeutic Strategies to Overcome Acquired Resistance to BRAF or MEK Inhibitors in BRAF Mutant Cancers

19 Apr 2011

Abstract excerpt

Ryan B. Corcoran 1,2 , Jeffrey Settleman 3 , Jeffrey A. Engelman 1,2 1 Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA 2 Department of Medicine, Harvard Medical School, Boston, MA 02115, USA 3 Genentech, South San Francisco, CA 94080, USA Keywords: BRAF, MEK; acquired resistance, melanoma, colorectal cancer, NRAS, IGF1R, PDGFR Received: April 15, 2011; Accepted: April 18, 2011; Published:...

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PMID: 21505228
DOI: 10.18632/oncotarget.262

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