Article
Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
American journal of clinical pathology - 1 May 2011
Huh Yang O, Schweighofer Carmen D, Ketterling Rhett P, Knudson Ryan A, Vega Francisco, Kim Ji E, Luthra Rajyalakshmi, Keating Michael J, Medeiros L Jeffrey, Abruzzo Lynne V
Abstract excerpt
The t(14;19)(q32;q13) involving the IGH@ and BCL3 loci is an infrequent cytogenetic abnormality detected in B-cell malignancies. We describe the clinicopathologic, cytogenetic, and molecular genetic characteristics of 14 cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with t(14;19)(q32;q13). All patients (10 men and 4 women) had lymphocytosis; 10 had lymphadenopathy. Blood and bone...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
