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Article

Regulation of influenza A virus induced CXCL-10 gene expression requires PI3K/Akt pathway and IRF3 transcription factor.

Molecular immunology - 1 Jul 2011

Lu Xinya, Masic Aleksandar, Liu Qiang, Zhou Yan

Abstract excerpt

Influenza A virus infects human airway epithelial cells, and induces the CXC chemokine gamma interferon (IFN-γ)-inducible protein CXCL-10/IP-10 production. To understand the regulation of CXCL-10, we investigated the role of PI3K/AKT pathway in regulating virus induced CXCL-10 production. Previously we have shown that wild type (WT) influenza A virus infection activates PI3K/AKT pathway, whereas PR8-SH3-mf-1...

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Identifiers

PMID: 21497908
DOI: 10.1016/j.molimm.2011.03.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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