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Article

COMT polymorphism and the risk of endometriosis-related infertility.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Dec 2011

Christofolini Denise Maria, Teles Juliana Souto, Vilarino Fábia Lima, André Gustavo Mendonça, Bianco Bianca, Barbosa Caio Parente

Abstract excerpt

Estrogens are important factors in the development of endometriosis, and can induce cell proliferation and stimulate cell division. COMT constitutes a crucial element in estrogen metabolism and has been suggested to be involved in the development of endometriosis. This study had the objective of...

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Source

Identifiers

PMID: 21495799
DOI: 10.3109/09513590.2011.569797

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21495799-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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COMT polymorphism and the risk of endometriosis-related infertility.PMID 21495799Read ↗

COMT polymorphism influences decrease of ovarian follicles and emerges as a predictive factor for premature ovarian insufficiency.Semantic proximity Read ↗

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The association between CYP19 polymorphism and endometriosis risk: a system review and meta-analysis.Semantic proximity Read ↗

COMT 158G/A and CYP1B1 432C/G polymorphisms increase the risk of endometriosis and adenomyosis: a meta-analysis.Semantic proximity Read ↗

Investigation of polymorphisms in genes involved in estrogen metabolism in menstrual migraine.Semantic proximity Read ↗

Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density.Semantic proximity Read ↗

The catechol-O-methyltransferase (COMT) gene polymorphism and prevalence of uterine fibroids.Semantic proximity Read ↗

[The risk of endometrial cancer appearance and CYP19 and COMT gene polymorphism].Semantic proximity Read ↗

Lack of associations of the COMT Val158Met polymorphism with risk of endometrial and ovarian cancer: a pooled analysis of case-control studies.Semantic proximity Read ↗

Catechol-O-methyltransferase (COMT) single nucleotide polymorphisms and haplotypes are not major risk factors for polycystic ovary syndrome.Semantic proximity Read ↗

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