Article
Screening SNPs residing in the microRNA-binding sites of hepatocellular carcinoma related genes.
International journal of data mining and bioinformatics - 1 Jan 2011
Ding Jun, Gao Yuzhen, He Yan, Zhou Yifeng, Huang Moli, Liu Haiyan
Abstract excerpt
Single nucleotide polymorphisms located at miRNA-binding sites are likely to affect the expression of the miRNA targets and may contribute to the susceptibility of humans to common diseases. Here we selected 289 candidate Hepatocellular Carcinoma (HCC) related genes according to the existing literature and database. We identified putative miRNA-binding sites of 52 genes by specialised algorithms, screened SNPs in...
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