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The Properties of Red Blood Cells from Patients Heterozygous for HbS and HbC (HbSC Genotype)

13 Oct 2010

Abstract excerpt

Sickle cell disease (SCD) is one of the commonest severe inherited disorders, but specific treatments are lacking and the pathophysiology remains unclear. Affected individuals account for well over 250,000 births yearly, mostly in the Tropics, the USA, and the Caribbean, also in Northern Europe as well. Incidence in the UK amounts to around 12-15,000 individuals and is increasing, with approximately 300 SCD...

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PMID: 21490760
DOI: 10.1155/2011/248527

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