Article
A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus.
Molecular biology of the cell - 1 Jun 2011
Wong Sak Hoi Joanne, Lamarre Claude, Beau Rémi, Meneau Isabelle, Berepiki Adokiye, Barre Annick, Mellado Emilia, Read Nick D, Latgé Jean-Paul
Abstract excerpt
During a search for genes controlling conidial dormancy in Aspergillus fumigatus, two dehydrin-like genes, DprA and DprB, were identified. The deduced proteins had repeated stretches of 23 amino acids that contained a conserved dehydrin-like protein (DPR) motif. Disrupted DprAΔ mutants were hypersensitive to oxidative stress and to phagocytic killing, whereas DprBΔ mutants were impaired in osmotic and pH stress...
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