Article
Frequency distribution of HLA DQ2 and DQ8 in celiac patients and first-degree relatives in Recife, northeastern Brazil.
Clinics (Sao Paulo, Brazil) - 1 Jan 2011
Castro-Antunes Margarida Maria, Crovella Sergio, Brandão Lucas Andre Cavalcanti, Guimaraes Rafael Lima, Motta Maria Eugênia Farias Almeida, Silva Giselia Alves Pontes da
Abstract excerpt
AIMS: The aim of this study was to evaluate the frequencies of the HLA genotypes DQ2 and DQ8 and the alleles A1*05, A1*0201, B1*0201 and B1*0302 in individuals with celiac disease in Recife, northeastern Brazil. METHODS: HLA DQ2 and DQ8 genotyping was performed for 73 individuals with celiac disease and 126 first-degree relatives with negative transglutaminase serology. The alleles DQA1*05, DQA1*0201, DQB1*02 and...
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