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Article

Influence of the HLA-DRB1 genotype on antibody development to interferon beta in multiple sclerosis.

Archives of neurology - 1 Apr 2011

Buck Dorothea, Cepok Sabine, Hoffmann Steve, Grummel Verena, Jochim Angela, Berthele Achim, Hartung Hans-Peter, Wassmuth Ralf, Hemmer Bernhard

Abstract excerpt

OBJECTIVE: To determine relevant HLA-DRB1 alleles associated with the susceptibility of anti-interferon beta antibody development in a large patient cohort. DESIGN: In a case-control study, HLA-DRB1 genotyping was performed in a discovery cohort (n = 268) and a validation cohort (n = 825). SETTING: Patients were recruited in Germany by primary care physicians and neurologists and were mainly of Northern European...

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Identifiers

PMID: 21482927
DOI: 10.1001/archneurol.2011.65

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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