Article
L-fucose utilization provides Campylobacter jejuni with a competitive advantage.
Proceedings of the National Academy of Sciences of the United States of America - 26 Apr 2011
Stahl Martin, Friis Lorna M, Nothaft Harald, Liu Xin, Li Jianjun, Szymanski Christine M, Stintzi Alain
Abstract excerpt
Campylobacter jejuni is a prevalent gastrointestinal pathogen in humans and a common commensal of poultry. When colonizing its hosts, C. jejuni comes into contact with intestinal carbohydrates, including L-fucose, released from mucin glycoproteins. Several strains of C. jejuni possess a genomic island (cj0480c-cj0490) that is up-regulated in the presence of both L-fucose and mucin and allows for the utilization...
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