Article
Molecular portraits of intratumoral heterogeneity in human ovarian cancer.
Cancer letters - 1 Aug 2011
Choi Yoon Pyo, Shim Hyo Sup, Gao Ming-Qing, Kang Suki, Cho Nam Hoon
Abstract excerpt
One of the most common characteristic profiles of cancer is intratumoral heterogeneity (ITH). We aimed to clarify the molecular profiles and biological significance of ITH with relation to cancer stem cell (CSC). We analyzed five primary cultured clones generated from different spatial zones, front and rear zone, of a fresh-frozen ovarian tumor tissue, performing ATP-CRA, conventional RT-PCR, side population (SP)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
