Article
Frequency and molecular basis of CD36 deficiency among platelet donors in Kunming, China.
Platelets - 1 Dec 2023
Lyu Qilu, Peng Mozhen, Chen Qiang, Ji Xin, Wang Zhijiang, Li Qian, Zhang Zhihui, Luo Zhen, Yin Yonghua, Su Pincan, Santoso Sentot, Wang Jue
Abstract excerpt
CD36 is a multifunctional receptor expressed on the surface of many cell types. Among healthy individuals, CD36 may be absent on platelets and monocytes (type I deficiency) or platelets alone (type II deficiency). However, the exact molecular mechanisms underlying CD36 deficiency remain unclear. In this study, we aimed to identify individuals with CD36 deficiency and investigate the molecular basis underlying it....
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