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Article

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.

Molecular genetics and metabolism - 1 Jul 2011

Olsson Anders H, Rönn Tina, Elgzyri Tarq, Hansson Ola, Eriksson Karl-Fredrik, Groop Leif, Vaag Allan, Poulsen Pernille, Ling Charlotte

Abstract excerpt

Type 2 diabetes patients exhibit a reduction in oxidative muscle fibres and an increase in glycolytic muscle fibres. In this study, we investigated whether both genetic and non-genetic factors influence the mRNA expression levels of three myosin heavy chain (MHC) genes represented in different fibre types. Specifically, we examined the MHC7 (slow-twitch oxidative fibre), MHCIIa (fast-twitch oxidative fibre) and...

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Identifiers

PMID: 21470888
DOI: 10.1016/j.ymgme.2011.03.017

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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