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Article

The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors).

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jan 2009

Lips D J, Barker N, Clevers H, Hennipman A

Abstract excerpt

BACKGROUND: Aggressive fibromatosis (syn. desmoid tumor) is a sporadically occurring neoplastic proliferation of fibroblasts originating from musculoaponeurotic planes, forming invasively growing masses without the capability to metastasize. The choice of treatment remains surgical resection with or without radiotherapy, and is characterized by high recurrence rates. Better understanding of the aetiology of...

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Share to Adenomatous Polyposis Coli Protein
Share to beta Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Desmoid Tumors

Share to APC gene

Share to Gene Expression Regulation, Neoplastic

Share to Genes, APC

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Source

Identifiers

PMID: 18722078
DOI: 10.1016/j.ejso.2008.07.003

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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