Article
Cdc1p is a Golgi-localized glycosylphosphatidylinositol-anchored protein remodelase.
Molecular biology of the cell - 15 Dec 2020
Yang Gege, Banfield David K
Abstract excerpt
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) undergo extensive posttranslational modifications and remodeling, including the addition and subsequent removal of phosphoethanolamine (EtNP) from mannose 1 (Man1) and mannose 2 (Man2) of the glycan moiety. Removal of EtNP from Man1 is catalyzed by Cdc1p, an event that has previously been considered to occur in the endoplasmic reticulum (ER). We establish...
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