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Article

Cerebrovascular atherosclerosis in type III hyperlipidemia is modulated by variation in the apolipoprotein A5 gene.

European journal of medical research - 24 Feb 2011

Evans D, Bode A, von der Lippe G, Beil F U, Mann W A

Abstract excerpt

OBJECTIVE: Type III Hyperlipoproteinemia is a rare lipid disorder with a frequency of 1-5 in 5000. It is characterized by the accumulation of triglyceride rich lipoproteins and patients are at increased risk of developping atherosclerosis. Type III HLP is strongly associated with the homozygous presence of the ε2 allele of the APOE gene. However only about 10% of subjects with APOE2/2 genotype develop...

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Source

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Identifiers

PMID: 21463987
DOI: 10.1186/2047-783x-16-2-79
PMCID: PMC3353427

Genes

APOA5
APOC3
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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