Article
Apolipoprotein A5 gene IVS3+G476A allelic variant confers susceptibility for development of ischemic stroke.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jul 2008
Maasz Anita, Kisfali Peter, Jaromi Luca, Horvatovich Katalin, Szolnoki Zoltan, Csongei Veronika, Safrany Eniko, Sipeky Csilla, Hadarits Ferenc, Melegh Bela
Abstract excerpt
BACKGROUND: T-1131C, T1259C and IVS3+G476A are naturally occurring variants of the apolipoprotein A5 (APOA5) gene and their possible impact on the development of ischemic stroke was investigated in the present study. METHODS AND RESULTS: PCR-RFLP assays were used to determine the distributions of the APOA5 alleles in small-vessel, large-vessel and mixed subgroups of 378 patients and in 131 stroke-free control...
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