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The p53‐, Bax‐ and p21‐dependent inhibition of colon cancer cell growth by 5‐hydroxy polymethoxyflavones

23 Nov 2010

Abstract excerpt

SCOPE: Previously, we reported that 5-hydroxy polymethoxyflavones (5OH-PMFs) isolated from orange, namely 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone, 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone (5HHMF) and 5-hydroxy-6,7,8,4'-tetramethoxyflavone (5HTMF), potently induced apoptosis and cell-cycle arrest in multiple human colon cancer cells. Herein, using isogenic variants of HCT116 human colon cancer cells, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21462329
DOI: 10.1002/mnfr.201000269

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