Article
Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Oct 2011
Lin Lin, Shen Qi, Zhang Chenguang, Chen Lianxu, Yu Changlong
Abstract excerpt
MicroRNA has an important role in regulating gene expression during cell differentiation. In this study we identified the expression pattern of microRNA in the differentiated and dedifferentiated chondrocytes. Adult human articular chondrocytes were cultured in monolayer. RNA was isolated from the differentiated chondrocytes (collected after isolation) and the fifth-passage (dedifferentiated) chondrocytes, and...
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