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Article

Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis.

Journal of virology - 1 Jun 2011

Palgrave Christopher J, Gilmour Linzi, Lowden C Stewart, Lillico Simon G, Mellencamp Martha A, Whitelaw C Bruce A

Abstract excerpt

African swine fever virus (ASFV) is a highly infectious disease of domestic pigs, with virulent isolates causing a rapidly fatal hemorrhagic fever. In contrast, the porcine species endogenous to Africa tolerate infection. The ability of the virus to persist in one host while killing another genetically related host implies that disease severity may be, in part, modulated by host genetic variation. To complement...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21450812
DOI: 10.1128/JVI.00331-11
PMCID: PMC3126315

Genes

RELA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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