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Article

Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.

Pharmacogenomics - 1 Mar 2011

Lamba Jatinder K, Crews Kristine R, Pounds Stanley B, Cao Xueyuan, Gandhi Varsha, Plunkett William, Razzouk Bassem I, Lamba Vishal, Baker Sharyn D, Raimondi Susana C, Campana Dario, Pui Ching-Hon, Downing James R, Rubnitz Jeffrey E, Ribeiro Raul C

Abstract excerpt

AIM: To identify gene-expression signatures predicting cytarabine response by an integrative analysis of multiple clinical and pharmacological end points in acute myeloid leukemia (AML) patients. MATERIALS & METHODS: We performed an integrated analysis to associate the gene expression of diagnostic bone marrow blasts from acute myeloid leukemia (AML) patients treated in the discovery set (AML97; n = 42) and in...

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Share to Antimetabolites, Antineoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 21449673
DOI: 10.2217/pgs.10.191
PMCID: PMC3139433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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