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Article

Lipase maturation factor 1 is required for endothelial lipase activity.

Journal of lipid research - 1 Jun 2011

Ben-Zeev Osnat, Hosseini Maryam, Lai Ching-Mei, Ehrhardt Nicole, Wong Howard, Cefalù Angelo B, Noto Davide, Averna Maurizio R, Doolittle Mark H, Péterfy Miklós

Abstract excerpt

Lipase maturation factor 1 (Lmf1) is an endoplasmic reticulum (ER) membrane protein involved in the posttranslational folding and/or assembly of lipoprotein lipase (LPL) and hepatic lipase (HL) into active enzymes. Mutations in Lmf1 are associated with diminished LPL and HL activities ("combined...

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Source

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Identifiers

PMID: 21447484
DOI: 10.1194/jlr.M011155
PMCID: PMC3090237

Genes

LPL
LMF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21447484-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Lipase maturation factor 1 is required for endothelial lipase activity.PMID 21447484Read ↗

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A quantitative assay measuring the function of lipase maturation factor 1.Semantic proximity Read ↗

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Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum.Semantic proximity Read ↗

Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia.Semantic proximity Read ↗

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