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Article

A Compound Heterozygous Mutation of Lipase Maturation Factor 1 is Responsible for Hypertriglyceridemia of a Patient.

Journal of atherosclerosis and thrombosis - 1 Feb 2019

Liu Yihui, Xu Jiang, Tao Wanyun, Yu Rong, Zhang Xinjiang

Abstract excerpt

AIM: Dyslipidemia is the most common lipid metabolism disorder in humans, and its etiology remains elusive. Hypertriglyceridemia (HTG) is a type of dyslipidemia that contributes to atherosclerosis and coronary heart disease. Previous studies have demonstrated that mutations in lipoprotein lipase (LPL), apolipoprotein CII (APOC2), apolipoprotein AV (APOA5), glycosylphosphatidylinositol anchored high-density...

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Source

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Identifiers

PMID: 29910226
DOI: 10.5551/jat.44537
PMCID: PMC6365152

Genes

LMF1
LPL
APOA5
APOC2
GPD1
GPIHBP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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