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Article

Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum.

The Journal of biological chemistry - 27 Nov 2009

Doolittle Mark H, Neher Saskia B, Ben-Zeev Osnat, Ling-Liao Jo, Gallagher Ciara M, Hosseini Maryam, Yin Fen, Wong Howard, Walter Peter, Péterfy Miklós

Abstract excerpt

Lipase maturation factor 1 (LMF1) is predicted to be a polytopic protein localized to the endoplasmic reticulum (ER) membrane. It functions in the post-translational attainment of enzyme activity for both lipoprotein lipase and hepatic lipase. By using transmembrane prediction methods in mouse and human orthologs, models of LMF1 topology were constructed and tested experimentally. Employing a tagging strategy...

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Identifiers

PMID: 19783858
DOI: 10.1074/jbc.M109.049395
PMCID: PMC2785204

Genes

LMF1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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