Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipase maturation factor 1: structure and role in lipase folding and assembly.

Current opinion in lipidology - 1 Jun 2010

Doolittle Mark H, Ehrhardt Nicole, Péterfy Miklós

Abstract excerpt

PURPOSE OF REVIEW: Lipase maturation factor 1 (LMF1) is a membrane-bound protein located in the endoplasmic reticulum. It is essential to the folding and assembly (i.e., maturation) of a selected group of lipases that include lipoprotein lipase, hepatic lipase and endothelial lipase. The purpose of this review is to examine recent studies that have begun to elucidate the structure and function of LMF1 and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease
Share to Lipase
Share to Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Protein Binding

Share to Protein Folding

Source

Open in PubMed Open full text

Identifiers

PMID: 20224398
DOI: 10.1097/MOL.0b013e32833854c0
PMCID: PMC3924775

Genes

LMF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipase maturation factor 1: structure and role in lipase folding and assembly.PMID 20224398Read ↗

Lipase maturation factor 1: a lipase chaperone involved in lipid metabolism.Semantic proximity Read ↗

Lipase maturation factor LMF1, membrane topology and interaction with lipase proteins in the endoplasmic reticulum.Semantic proximity Read ↗

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia.Semantic proximity Read ↗

Lipase maturation factor 1 is required for endothelial lipase activity.Semantic proximity Read ↗

Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans.Semantic proximity Read ↗

A quantitative assay measuring the function of lipase maturation factor 1.Semantic proximity Read ↗

Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation.Semantic proximity Read ↗

Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemia.Semantic proximity Read ↗

Characterization of two novel pathogenic variants at compound heterozygous status in lipase maturation factor 1 gene causing severe hypertriglyceridemia.Semantic proximity Read ↗

Concept of lipid droplet biogenesisSemantic proximity Read ↗

New rare genetic variants of LMF1 gene identified in severe hypertriglyceridemia.Semantic proximity Read ↗

Homozygous variant in LMF-1 identified in 3 Colombian families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.