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Article

A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.

European journal of nutrition - 1 Feb 2012

Miller Rosalind J, Jackson Kim G, Dadd Tony, Nicol Beate, Dick Joanne L, Mayes Andrew E, Brown A Louise, Minihane Anne M

Abstract excerpt

PURPOSE: Green tea is thought to possess many beneficial effects on human health. However, the extent of green tea polyphenol biotransformation may affect its proposed therapeutic effects. Catechol-O-methyltransferase (COMT), the enzyme responsible for polyphenolic methylation, has a common polymorphism in the genetic code at position 158 reported to result in a 40% reduction in enzyme activity in in vitro...

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Source

Identifiers

PMID: 21445620
DOI: 10.1007/s00394-011-0189-0

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.PMID 21445620Read ↗

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