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Efficient Cellular Release of Rift Valley Fever Virus Requires Genomic RNA

21 Mar 2011

Abstract excerpt

The Rift Valley fever virus is responsible for periodic, explosive epizootics throughout sub-Saharan Africa. The development of therapeutics targeting this virus is difficult due to a limited understanding of the viral replicative cycle. Utilizing a virus-like particle system, we have established roles for each of the viral structural components in assembly, release, and virus infectivity. The envelope...

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PMID: 21445316
DOI: 10.1371/journal.pone.0018070

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