Article
Influence of anticancer therapy on oxidation phenotype and acetylation phenotype in patients with acute myeloblastic leukemia.
Pharmacological reports : PR - 1 Jan 2011
Łapiński Łukasz, Orzechowska-Juzwenko Krystyna, Wiela-Hojeńska Anna, Wołowiec Dariusz, Ganczarski Grzegorz, Głowacka Krystyna, Czarnik-Matusewicz Henryk, Kuliczkowski Kazimierz, Gąsiorowski Jacek
Abstract excerpt
The aim of this study was to determine whether antineoplastic cytostatic therapy induces changes in the oxidation or acetylation phenotypes in patients with acute myeloblastic leukemia (AML). The investigations involved 22 patients with AML undergoing chemotherapy with daunorubicin, cytosine arabinoside, etoposide and mitoxantrone. The oxidation phenotype prior to therapy and after termination of induction was...
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