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Article

Cross-protective TH1 immunity against Aspergillus fumigatus and Candida albicans

27 Mar 2011

Abstract excerpt

T cell-mediated heterologous immunity to different pathogens is promising for the development of immunotherapeutic strategies. Aspergillus fumigatus and Candida albicans, the 2 most common fungal pathogens causing severe infections in immunocompromised patients, are controlled by CD4+ type 1 helper T (T(H)1) cells in humans and mice, making induction of fungus-specific CD4+ T(H)1 immunity an appealing strategy...

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Identifiers

PMID: 21441461
DOI: 10.1182/blood-2010-12-325084

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