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Article

Association between plasma hepatocyte growth factor and gefitinib resistance in patients with advanced non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2011

Han Ji-Youn, Kim Jin Young, Lee Suk Hyung, Yoo Nam Jin, Choi Byung Gil

Abstract excerpt

PURPOSE: It has been suggested that hepatocyte growth factor (HGF) and insulin-like growth factor binding protein (IGFBP)-3 are associated with gefitinib resistance in non-small cell lung cancer (NSCLC). We investigated the predictive and prognostic roles of these proteins in NSCLC patients treated with gefitinib. PATIENTS AND METHODS: Of 106 patients enrolled in a randomized phase II study of gefitinib, 97 had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21440951
DOI: 10.1016/j.lungcan.2011.02.021

Genes

HGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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