Article
Evaluation of the level of Mx3 protein synthesis induced by infectious pancreatic necrosis virus (IPNV) strains of different infectivity.
Veterinary immunology and immunopathology - 15 Jun 2011
Ortega César, Rodríguez Sylvia, de las Heras Ana I, Romero Alex, Monrás Mónica, Enríquez Ricardo
Abstract excerpt
The in vitro infectivity and genotype of three IPNV strains (V70, V112 and V98) was linked to the level of transcript synthesis for the Mx3 protein in RTG-2 (Rainbow trout gonad) cells and in Salmo salar. The V70 and V98 strains corresponded to the Sp genotype, whilst the V112 corresponded to VR-299; the presence of Pro-217 and Ala-221 in VP2 identified V70 as a strain of medium virulence level whilst V112...
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