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Article

Ex vivo expansion of human hematopoietic stem and progenitor cells

25 Mar 2011

Abstract excerpt

Despite progress in our understanding of the growth factors that support the progressive maturation of the various cell lineages of the hematopoietic system, less is known about factors that govern the self-renewal of hematopoietic stem and progenitor cells (HSPCs), and our ability to expand human HSPC numbers ex vivo remains limited. Interest in stem cell expansion has been heightened by the increasing...

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PMID: 21436068
DOI: 10.1182/blood-2011-01-283606

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