Article
Modification of PCV-2 virulence by substitution of the genogroup motif of the capsid protein.
Veterinary research - 24 Mar 2011
Allemandou Aude, Grasland Béatrice, Hernandez-Nignol Anne-Cécile, Kéranflec'h André, Cariolet Roland, Jestin André
Abstract excerpt
Porcine circovirus type 2 (PCV-2) is the causal agent of the post-weaning multisystemic wasting syndrome (PMWS). PCV-2 are small single-stranded circular DNA viruses clustered into two main genogroups: PCV-2a and PCV-2b. Each genogroup present a specific highly-conserved motif of six amino acids (between amino acids 86 and 91) in the PCV-2 capsid protein. The aim of this study was to verify whether the motif...
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