Article
A porcine circovirus-2 mutant isolated in Brazil contains low-frequency substitutions in regions of immunoprotective epitopes in the capsid protein.
Archives of virology - 1 Nov 2015
Salgado Rafael Locatelli, Vidigal Pedro Marcus Pereira, Gonzaga Natalia F, de Souza Luiz F L, Polêto Marcelo D, Onofre Thiago Souza, Eller Monique R, Pereira Carlos Eduardo Real, Fietto Juliana L R, Bressan Gustavo C, Guedes Roberto M C, Almeida Márcia R, Silva Júnior Abelardo
Abstract excerpt
Porcine circovirus-2 (PCV2) is the etiologic agent of several diseases in pigs, including multi-systemic wasting syndrome (PMWS). In this work, a new mutant PCV2b was isolated from PMWS-affected pigs on a Brazilian farm. Its genome showed high sequence similarity (>99% identity) to those from a group of emerging mutants isolated from cases of PMWS outbreaks in vaccinated pigs in China, the USA and South Korea....
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