Article
Mutant USA strain of porcine circovirus type 2 (mPCV2) exhibits similar virulence to the classical PCV2a and PCV2b strains in caesarean-derived, colostrum-deprived pigs.
The Journal of general virology - 1 Nov 2014
Opriessnig Tanja, Xiao Chao-Ting, Gerber Priscilla F, Halbur Patrick G, Matzinger Shannon R, Meng Xiang-Jin
Abstract excerpt
In 2012, a mutant porcine circovirus type 2 (mPCV2) strain was identified in cases of PCV-associated disease (PCVAD) in the USA. The mPCV2 had an additional amino acid, lysine (K), in the capsid at position 234. The objectives of this study were to compare the pathogenicity of mPCV2, PCV2a and PCV2b in pigs using biologically pure infectious virus stocks derived from respective infectious DNA clones, and to...
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