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The Role of Macrophages in the Host’s Defense against Sporothrix schenckii

18 Jul 2021

Abstract excerpt

The role of immune cells associated with sporotrichosis caused by Sporothrix schenckii is not yet fully clarified. Macrophages through pattern recognition receptors (PRRs) can recognize pathogen-associated molecular patterns (PAMPs) of Sporothrix, engulf it, activate respiratory burst, and secrete pro-inflammatory or anti-inflammatory biological mediators to control infection. It is important to consider that the...

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PMID: 34358055
DOI: 10.3390/pathogens10070905

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