Article
Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges.
Molecular ecology resources - 1 Mar 2011
Helyar S J, Hemmer-Hansen J, Bekkevold D, Taylor M I, Ogden R, Limborg M T, Cariani A, Maes G E, Diopere E, Carvalho G R, Nielsen E E
Abstract excerpt
Recent improvements in the speed, cost and accuracy of next generation sequencing are revolutionizing the discovery of single nucleotide polymorphisms (SNPs). SNPs are increasingly being used as an addition to the molecular ecology toolkit in nonmodel organisms, but their efficient use remains challenging. Here, we discuss common issues when employing SNP markers, including the high numbers of markers typically...
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