Article
In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes.
Cell research - 1 Sept 2011
Cao Nan, Liao Jing, Liu Zumei, Zhu Wenmin, Wang Jia, Liu Lijun, Yu Lili, Xu Ping, Cui Chun, Xiao Lei, Yang Huang-Tian
Abstract excerpt
The recent breakthrough in the generation of rat embryonic stem cells (rESCs) opens the door to application of gene targeting to create models for the study of human diseases. In addition, the in vitro differentiation system from rESCs into derivatives of three germ layers will serve as a powerful tool and resource for the investigation of mammalian development, cell function, tissue repair, and drug discovery....
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