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Article

Activation of estrogen receptor alpha disrupts differentiation of the reproductive organs in chicken embryos.

General and comparative endocrinology - 1 Jun 2011

Mattsson Anna, Olsson Jan A, Brunström Björn

Abstract excerpt

Gonadal estrogen plays an important role in the differentiation of a female phenotype in birds. Exogenous compounds that interfere with estrogen signaling, for instance by binding to the estrogen receptors alpha and beta (ERα and ERβ), are therefore potential disruptors of sexual differentiation in birds. The ERα agonist propyl-pyrazole-triol (PPT), the ERα antagonist methyl piperidino pyrazole (MPP) and the ERβ...

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Identifiers

PMID: 21420409
DOI: 10.1016/j.ygcen.2011.03.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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