Article
[Relationship of the CDKAL1 and KCNQ1 gene polymorphisms to the age at diagnosis of type 2 diabetes in the Slovakian population].
Vnitrni lekarstvi - 1 Feb 2011
Dobríková M, Javorský M, Habálová V, Klimcáková L, Kozárová M, Zidzik J, Halusková J, Salagovic J, Tkác I
Abstract excerpt
BACKGROUND/AIMS: The association of CDKAL1 and KCNQ1 genes with type 2 diabetes mellitus (DM2T) was confirmed by several genome-wide association studies in both Caucasian and Asian populations. For both genes, it is supposed that the risk of DM2T development is related to impaired insulin secretion. Based on assumption that the presence of risk allele might predispose to an earlier onset of DM2T, the aim of the...
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