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Article

Involvement of Mouse Nucleoplasmin 2 in the Decondensation of Sperm Chromatin after Fertilization1

18 Mar 2011

Abstract excerpt

The tightly condensed chromatin of spermatozoa is rapidly decondensed after the spermatozoa enter oocytes. Although no factor involved in sperm chromatin decondensation (SCD) has been identified in mammals, it has been suggested that a factor related to SCD activity is present in the germinal vesicle (GV) of oocytes. Here, we found that the nucleolus-like body (NLB), which is a component of the GV, is involved in...

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PMID: 21415138
DOI: 10.1095/biolreprod.110.089342

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