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Article

Association between MTHFR 1298A>C polymorphism and spontaneous abortion with fetal chromosomal aneuploidy.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Oct 2011

Kim Shin Young, Park So Yeon, Choi Ji Won, Kim Do Jin, Lee Shin Yeong, Lim Ji Hyae, Han Jung Yeol, Ryu Hyun Mee, Kim Min Hyoung

Abstract excerpt

PROBLEM Polymorphisms in genes involved in folate metabolism are commonly associated with defects in folate-dependent homocysteine metabolism, which can result in DNA hypomethylation and chromosome nondisjunction. This prospective study aimed to investigate the associations between MTHFR 677C>T, MTHFR 1298A>C, MTR 2756A>G, MTRR 66A>G, and CBS 844ins68 polymorphisms and spontaneous abortion (SA) with fetal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21410812
DOI: 10.1111/j.1600-0897.2011.00996.x

Genes

MTHFR
CBS
MTR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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