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Article

Simultaneous aberrations of single CDKN2A network components and a high Rb phosphorylation status can differentiate subgroups of primary cutaneous B-cell lymphomas.

Experimental dermatology - 1 Apr 2011

Kaune Kjell M, Neumann Christine, Hallermann Christian, Haller Florian, Schön Michael P, Middel Peter

Abstract excerpt

The cyclin-dependent kinase inhibitor 2A (CDKN2A) gene on chromosome 9p21 encodes p16 (INK4A), the inhibitor of the CDK4/retinoblastoma (Rb) cell proliferation pathway, as well as p14 (ARF), which controls p53-dependent pathways. Inactivation of p16 has previously been associated with the prognostically unfavourable primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL, LT). In this work, we analysed...

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Share to Chromosomes, Human, Pair 13
Share to Genes, p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Retinoblastoma

Share to Lymphoma, B-Cell, Marginal Zone

Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Tumor Suppressor Protein p14ARF

Source

Identifiers

PMID: 21410763
DOI: 10.1111/j.1600-0625.2010.01226.x

Genes

CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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