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Article

High Incidence and Clinical Significance of MYC Rearrangements in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type.

The American journal of surgical pathology - 1 Nov 2018

Schrader Anne M R, Jansen Patty M, Vermeer Maarten H, Kleiverda Johanna K, Vermaat Joost S P, Willemze Rein

Abstract excerpt

Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) and primary cutaneous follicle center lymphoma (PCFCL) are cutaneous B-cell lymphomas (CBCL) with different clinical characteristics and behavior. PCDLBCL-LT is the most aggressive CBCL with a relatively poor prognosis. In nodal diffuse large B-cell lymphoma (DLBCL), rearrangements of the MYC gene, especially in combination with a second hit...

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Topics

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Share to Databases, Factual
Share to Gene Rearrangement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

Share to Proto-Oncogene Proteins c-myc

Source

Identifiers

PMID: 30113335
DOI: 10.1097/PAS.0000000000001132

Genes

MYC
BCL2
BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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