Article
A phosphatidate phosphatase double mutant provides a new insight into plant membrane lipid homeostasis.
Plant signaling & behavior - 1 Apr 2011
Eastmond Peter J, Quettier Anne-Laure, Kroon Johan T, Craddock Christian, Adams Nicolette, Slabas Antoni R
Abstract excerpt
Phospholipids make up the bulk of most eukaryotic cell membranes, but how their synthesis is regulated remains relatively poorly understood in plants. In our article1 we provide evidence that two Mg ( 2+) -dependent phosphatidic acid phosphatase enzymes, called PAH1 and PAH2, are capable of repressing phospholipid biosynthesis at the endoplasmic reticulum in Arabidopsis thaliana. The precise mechanism of...
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