Article
Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration.
Developmental cell - 1 Jul 2004
Somogyi Kálmán, Rørth Pernille
Abstract excerpt
Cells migrating through a tissue exert force via their cytoskeleton and are themselves subject to tension, but the effects of physical forces on cell behavior in vivo are poorly understood. Border cell migration during Drosophila oogenesis is a useful model for invasive cell movement. We report that this migration requires the activity of the transcriptional factor serum response factor (SRF) and its cofactor...
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