Article
Genetic and molecular exploration of UHMK1 in schizophrenic patients.
Psychiatric genetics - 1 Dec 2011
Dumaine Anne, Maucuer Alexandre, Barbet Aurélie, Manceau Valérie, Deshommes Jasmine, Méary Alexandre, Szöke Andrei, Schürhoff Franck, Llorca Pierre-Michel, Lancon Christophe, Leboyer Marion, Jamain Stéphane
Abstract excerpt
In two recent papers, polymorphisms located in U2AF homology motif kinase 1 (UHMK1) gene have been associated to schizophrenia. This gene encodes the serine/threonine kinase, kinase interacting with Stathmin, and has been functionally related to RNA metabolism and neurite outgrowth. In this study, we explored the contribution of this gene in schizophrenia susceptibility, using a case-control association study, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.