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Article

No association of mutations and mRNA expression of WFS1/wolframin with bipolar disorder in humans.

Neuroscience letters - 20 Feb 2003

Kato Tadafumi, Iwamoto Kazuya, Washizuka Shinsuke, Mori Kanako, Tajima Osamu, Akiyama Tsuyoshi, Nanko Shinichiro, Kunugi Hiroshi, Kato Nobumasa

Abstract excerpt

Association of WFS1 (wolframin) and bipolar disorder has been suggested by psychiatric manifestations in patients or non-symptomatic carriers of Wolfram disease and linkage of bipolar disorder with 4p16, the locus of WFS1. Five studies of WFS1 in bipolar disorder did not support this association, although possible association of several missense mutations has not been excluded yet. In this study, four such...

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PMID: 12565131
DOI: 10.1016/s0304-3940(02)01334-4

Genes

WFS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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